The effectiveness and safety of cranial nerve block in migraine: a critical review

Cranial nerve blocks (CNBs) have been used for the acute and preventive treatment of a variety headaches, including migraine. The effectiveness CNBs in migraine is usually observed beyond duration block, possibly due to central pain modulation. most target greater occipital nerve. Other commonly targeted nerves are lesser various branches trigeminal nerve, supratrochlear, supraorbital, auriculotemporal nerves. generally safe well-tolerated procedures that can be performed either emergency or outpatient settings. There currently no guideline standardizing In clinical practice, as well few published studies, results encouraging, justifying further studies area. present study we critically review literature about safety efficacy attacks